Research progress of traditional Chinese medicine influencing macrophage polarization

GAO Shuang,CHEN Zhesheng,…, LI Jing*
[Abstract] Recently, with advancements in science and technology, humans have found that macrophages play essential roles in many diseases, which has become a new focus of research on disease diagnosis and treatment. As traditional Chinese medicine is one of the main tools for disease prevention and treatment, research on its macrophage polarization deserves attention. In this paper, we summarized the effects of traditional Chinese medicine on macrophage polarization in areas such as inhibition of M1 macrophage polarization, inhibition of M2 polarization, and effects on reversal of M1/M2 macrophage phenotype.

[Key words] Traditional Chinese medicine; Macrophages; Polarization; M1 macrophage; M2 macrophage

中医药影响巨噬细胞极化的研究进展

[摘要]近年来，随着科学技术的发展，人们发现巨噬细胞在许多疾病中都发挥着重要作用，成为疾病诊疗研究的新的出发点。中医药作为疾病防治的主要手段之一，在巨噬细胞极化方面的研究值得关注。本文从抑制M1型巨噬细胞方向极化、抑制M2型巨噬细胞方向极化及影响M1/M2型巨噬细胞表型逆转方面，概述了中医药对巨噬细胞极化的影响。

[关键词]中医药； 巨噬细胞； 极化； M1型巨噬细胞； M2型巨噬细胞