Drug development is a lengthy process associated with tremendous cost and high failure rate. On average, less than 1 in 10 drug candidates are eventually approved by the Food and Drug Administration. These high failure/attrition ratios of drugs in human patients are mainly attributed to the inefficient validation based on planar static cell cultures and preclinical animal models for establishing drug efficacy and safety. Therefore, there is an urgent need for the development of viable platforms for drug evaluation.
Biomarkers have been utilized for improving the benefit/risk ratios of drugs and the efficiency of drug development and are becoming more and more important in the process of drug research and development. Biosensors are analytical tools that can convert analyte recognition events into readily detectable readout signals, and have been developed for the detection of many different analytes, such as ions, small molecules, proteins, enzymes, and cells. Thus, we can improve the efficiency of drug research and development by precisely and rapidly detecting the biomarkers through the technology of biosensors. The biological sensitive receptor integrated with the physicochemical energy converter by biosensors for drug analysis, research and development also embodies an application of the Holistic Integrative Pharmacy.
Consequently, Professor Peng Zhao of Southern Medical University, Associate Professor Huijuan Yu of Guangdong University of Technology, and Associate Professor Duanping Sun of Guangdong Pharmaceutical University are the guest editors for the second issue of Journal of Holistic Integrative Pharmacy (JHIP) in 2022 to create a special issue on biosensors for drug research and development.
The journal is soliciting high-quality articles on this topic from experts in the relevant field both locally and abroad.
Call for papers! Research topic:
Biosensors for drug research and development: Emerging trends and prospects
Web address: https://jhip.gdpu.edu.cn/
E-mail: hip2063@gdpu.edu.cn
Tel.: 020-39352063
